The Greenland Shark Genome: The Secret of 400 Years of Life Revealed
The Greenland shark is the longest-living vertebrate on Earth, with estimates of up to 400 years. Now, an international team led by the University of ...
DNA
DNA, genetics and damage repair
SIRT6 Protein Reversed the Aging Clock in the Livers of Old Mice
Once every few years, a study is published that moves the entire field forward, and this time it came from Israel. A team of researchers from Bar-Ilan...
Klotho Protein: The Longevity Protein Most of You Haven't Heard Of
The Greek goddess Clotho was one of the three Moirai, fates who spun the thread of human life. When Japanese scientists discovered in 1997 a protein w...
DeepMind and Aging: Artificial Intelligence Identifies Genes That Reverse Cells
The two great revolutions of the decade, artificial intelligence and the biology of aging, finally meet in the same room. On May 20, 2026, Google Deep...
DNA Damage Theory Collapses: Aging is an Epigenetic Problem
For nearly 50 years, the dominant explanation for biological aging was simple: the accumulation of DNA damage over a lifetime wears down our cells, ca...
APOE2 and DNA Repair: A Rare Genetic Variant Reveals How Neurons Resist Aging
Among all the genes that influence human longevity, there is arguably none more deeply studied than APOE. This gene, which encodes apolipoprotein E an...
What a 392-Year-Old Shark and a 211-Year-Old Whale Can Teach Us About Longevity
While the oldest human on record reached 122, some animals live 5 times longer. A Greenland shark born in the same era as Washington is still alive. W...
New Theory: Decline in Glycolytic ATP Production Is the Root Cause of Aging
For decades, we have searched for the "cause" of aging. A new theory in Aging-US offers a simple but revolutionary answer: a decline in energy product...
The Genetic Correction of Aging: How DNA Editing Extended Mouse Lifespan by 140%
The Atlantic wrote that "this is what all this research was supposed to lead to": the development of a DNA editing drug for progeria. The team succeed...
Your Immune System Attacks You: A Discovery That Explains Accelerated Aging and Progeria
For years, we described progeria (accelerated aging in children) as a direct result of DNA damage. A new study offers a different interpretation: the ...
DNA repair
Aging is an inevitable process, but studies indicate a close connection between it and a decrease in the ability to repair DNA. As a result, DNA damag...
Genetic therapies: a promise to rejuvenate the body?
Aging is a natural process, but many strive to slow it down and improve their quality of life even in old age. Gene therapies offer an innovative appr...
September 2015 Liz was nervous.
September 2015 Liz was nervous. She was on a plane to Colombia, where she would undergo an untested gene therapy. She and her colleagues had spent two...
Guto kola: the herb that promises to lengthen the telomeres?
Gutu kola, also known as Brahmi, Hydrocotyl and Centella asiatica, is a perennial plant that grows in tropical and subtropical regions of Asia. The pl...
NAD+: A Miracle Anti-Aging Drug or an Unfulfilled Promise?
Aging is a natural and inevitable process, but it is accompanied by a gradual decline in physical, cognitive, and social function. In recent years, th...
DNA Damage: A Ticking Time Bomb in the Body
DNA (deoxyribonucleic acid) is the genetic material containing all the instructions necessary for the normal functioning of cells. It serves as a deta...
Errors During Gene Expression: Their Impact on Protein Production and Cell Function
Within every cell in our body lies a hidden world – the world of genes. These genes are segments of DNA, containing instructions for producing protein...
Telomere Shortening
Telomeres are complex nuclear structures located at the ends of chromosomes. They consist of repetitive DNA sequences (TTAGGG) and unique proteins, an...